Calvin Roskelley

PhD, University of British Columbia
Department of Cellular and Physiological Sciences

Dr. Roskelley's laboratory is focused on understanding the genes and their products involved in regulating tissue architecture in breast and ovarian carcinoma progression. They have developed specialized, 3-dimensional models that allow for the recapitulation of normal epithelial tissue architecture outside the body in a tissue culture dish. They are now modulating the expression and function of cell adhesion molecules in these cultures to determine how architectural disruption allows epithelial cells to break away from the original tumor and begin invading surrounding tissues. The Roskelley group is also determining the specific molecules that are involved in regulating this migratory switch in breast and ovarian tumor cells.

Co-principal Investigator Awards

French Scholars Lecture Series, Jacky G. Goetz, 2020

Jacky G. Goetz
Calvin Roskelley