Christian Giaume

PhD, Pasteur Institute, Paris
Collège de France

Dr. Christian Giaume (1951 - 2019) was a world leader in the biophysical and pharmacological properties of gap junction channels in brain glial cells. In 1986, he obtained his PhD under the supervision of Dr. Henri Korn at the Pasteur Institute (Paris, France). He was later promoted to Director of Research at the Centre National De La Recherche Scientique (CNRS).

For two decades Prof. Giaume's work mainly focused on the molecular constituents of glial gap junctions and connexins. His work has led him to propose that instead of a “glial syncytium”, astroglia is organized in networks that are plastic and exhibit a specific spatial organization. Consequently, neuroglial interactions that are generally viewed at single cell level have also to be considered as an interplay of neuronal and astroglial networking. He also studied the contribution of astroglial connexin channels in the control of synaptic plasticity in several mouse models of brain pathology such as Alzheimer’s and Parkinson’s disease, neuropathic pain, and sleep disorders.

He leads a research team titled “Junctional communication and neuro-glio-vascular interactions” at the Collège de France in Paris. Their research shows that connexin channels differ in the control of synaptic activity, plasticity, and in the integrity of the blood brain barrier. He is currently author and co-author of 134 peer-reviewed articles, many published in top journals including Science, Nature, Nature Reviews Neuroscience, PNAS and Neuron, with an H-index of 49 and more than 7,000 citations.  He passed away in April 2019.

Primary Recipient Awards

French Scholars Lecture Series, Christian Giaume, 2017

Christian Giaume
Christian Naus

International Visiting Research Scholars, Christian Giaume, 2013

Christian Giaume
Christian Naus

Co-principal Investigator Awards

Distinguished Scholars in Residence, Christian Naus, 2013

Christian Naus
Christian Giaume

At the Institute, Dr. Naus will organize a Knowledge Mobilization Workshop on Emerging Concepts in Stroke and Neuroprotection sponsored by the Canadian Stroke Network and the Institute. He will also strengthen and expand his current research program in Gap Junctions and Disease, and extend international collaborations. This includes hosting Dr. Christian Giaume from the College de France, who will be an International Visiting Scholar in 2014.

Wall Colloquia Abroad, Christian Naus, 2012

Christian Naus
Christian Giaume

The Role of Gap Junction Proteins in Health and Disease

Principal Investigator: Christian Naus, Director, Life Sciences Institute, Professor, Department of Cellular and Physiological Sciences, UBC; Christian Giaume, Director, CIRB, Collège de France.

The objective of this international colloquium to be held May 3-4, 2012 at the Collège de France, Paris, is to provide a timely gathering of the scientific community working in the field of “gap junctions,” intercellular channels with distinct cellular functions in health and disease.


Related Event

May 102018
French Scholars Lecture Series
This seminar will focus on the importance of the “other cell type” in the brain, the neuroglia, and their unique role in normal and diseased brain.
Apr 282014
International Research Colloquium
The Peter Wall Institute for Advanced Studies is hosting an International Research Colloquium to showcase the best and most innovative research by principal investigators of its...